ATTENTION:<\/strong><\/p>\n\n\n\n BEFORE YOU READ THE ABSTRACT OR CHAPTER ONE OF THE PROJECT TOPIC BELOW, PLEASE READ THE INFORMATION BELOW.THANK YOU!<\/strong><\/p>\n\n\n\n INFORMATION:<\/strong><\/p>\n\n\n\n YOU CAN GET THE COMPLETE PROJECT OF THE TOPIC BELOW. THE FULL PROJECT COSTS N5,000 ONLY. THE FULL INFORMATION ON HOW TO PAY AND GET THE COMPLETE PROJECT IS AT THE BOTTOM OF THIS PAGE. OR YOU CAN CALL: 08068231953, 08168759420<\/strong><\/p>\n\n\n\n WHATSAPP US ON 08137701720<\/strong><\/p>\n\n\n\n THE EFFICACY IN THE USE OF BLOOD TRANSFUSSION IN MANAGING HAEMATOLOGICAL DISEASES<\/strong><\/p>\n\n\n\n CHAPTER ONE<\/p>\n\n\n\n INTRODUCTION<\/p>\n\n\n\n Background of the study<\/strong><\/p>\n\n\n\n Randomized clinical trials (RCTs) have determined, in surgical and critically ill patients, relatively safe hemoglobin (Hb) thresholds of 7-8 g\/dL to guide restrictive transfusion of red blood cells (RBCs). However, in patients with various hematologic disorders, strong evidence in support of such an approach is sparse and the optimal transfusion practice is yet to be defined. This review focuses on RBC transfusion practice in three hematologic diseases and a treatment strategy, including autoimmune hemolytic anemia, thalassemia, myelodysplastic syndrome, and hematopoietic stem cell transplantation. These entities manifest in a broad spectrum of anemia, acute or chronic, in patients with different comorbidities and degrees of transfusion requirement. Thus the nuances in the indications of RBC transfusion and the goals to achieve in these specific situations may have been underappreciated.<\/p>\n\n\n\n 1.2 Statement of the problem<\/strong><\/p>\n\n\n\n The limited data available highlight the importance of titrating RBC transfusion based on the clinical context and patient characteristics is a challenge. Future RCTs are necessary to firmly establish the Hb thresholds associated with improved outcomes relevant to these specific patient populations, which will facilitate the personalized decision-making in RBC transfusion.<\/p>\n\n\n\n 1.3 Learning Objectives<\/strong><\/p>\n\n\n\n \u25cf To understand the evidence supporting the current transfusion practice and its limitations in patients with hematologic disorders and anemia resulting from therapy<\/p>\n\n\n\n \u25cf To understand the goal(s) of red blood cell transfusion in patients with representative hematologic disorders and anemia resulting from therapy<\/p>\n\n\n\n 1.4 Research Questions<\/strong><\/p>\n\n\n\n 1. What is the evidence supporting the current transfusion practice and its limitations in patients with hematologic disorders and anemia resulting from therapy<\/p>\n\n\n\n 2. What are the goal(s) of red blood cell transfusion in patients with representative hematologic disorders and anemia resulting from therapy<\/p>\n\n\n\n 1.5 Research hypothesis<\/strong><\/p>\n\n\n\n H0: There is no significant impact of use of blood transfusion on patients with haematological diseases<\/p>\n\n\n\n H1: There is a significant impact of use of blood transfusion on patients with haematological diseases<\/p>\n\n\n\n HOW TO RECEIVE PROJECT MATERIAL(S)<\/strong><\/p>\n\n\n\n After paying the appropriate amount (#5,000) into our bank Account below, send the following information to<\/strong><\/p>\n\n\n\n 08068231953 or 08168759420<\/strong><\/p>\n\n\n\n (1) Your project topics<\/p>\n\n\n\n (2) Email Address<\/p>\n\n\n\n (3) Payment Name<\/p>\n\n\n\n (4) Teller Number<\/p>\n\n\n\n We will send your material(s) after we receive bank alert<\/p>\n\n\n\n BANK ACCOUNTS<\/strong><\/p>\n\n\n\n Account Name: AMUTAH DANIEL CHUKWUDI<\/p>\n\n\n\n Account Number: 0046579864<\/p>\n\n\n\n Bank: GTBank.<\/p>\n\n\n\n OR<\/p>\n\n\n\n Account Name: AMUTAH DANIEL CHUKWUDI<\/p>\n\n\n\n Account Number: 3139283609<\/p>\n\n\n\n Bank: FIRST BANK<\/p>\n\n\n\n FOR MORE INFORMATION, CALL:<\/strong><\/p>\n\n\n\n 08068231953 or 08168759420<\/strong><\/p>\n\n\n\n AFFILIATE LINKS:<\/a><\/p>\n\n\n\n myeasyproject.com.ng<\/a><\/p>\n\n\n\n easyprojectmaterials.com<\/a><\/p>\n\n\n\n easyprojectmaterials.net.ng<\/a><\/p>\n\n\n\n easyprojectsmaterials.net.ng<\/a><\/p>\n\n\n\n easyprojectsmaterial.net.ng<\/a><\/p>\n\n\n\n easyprojectmaterial.net.ng<\/a><\/p>\n\n\n\n projectmaterials.com.ng<\/a><\/p>\n\n\n\n